Resident Population in Karnes County, TX was 15.01800 Thous. of Persons in January of 2023, according to the United States Federal Reserve. Historically, Resident Population in Karnes County, TX reached a record high of 15.71500 in January of 2018 and a record low of 12.30400 in January of 1992. Trading Economics provides the current actual value, an historical data chart and related indicators for Resident Population in Karnes County, TX - last updated from the United States Federal Reserve on May of 2024.